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FDA review departments largely spared from Musk-led cuts

Since President Trump took office, Elon Musk's Department of Government Efficiency has laid off thousands of government workers through broad, sudden cuts — some later reversed — that have thrown the...

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Updated: Zealand partners with Roche on its amylin analog in a deal worth up...

Zealand Pharma has finally found a partner. And according to the Danish company, the licensing deal it announced with Roche on Wednesday for its amylin analog petrelintide is the biggest ever for an...

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Ono licenses rare blood disease drug from Ionis for $280M upfront

Ono Pharmaceutical is spending $280 million upfront to take the global rights of Ionis Pharmaceuticals’ asset for a rare blood disorder, marking the latest partnership for a disease space that has...

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Legend to double Carvykti production as it targets blockbuster status 

Unlocking manufacturing capacity will be key for Legend Biotech and Johnson and Johnson in achieving their goal of reaching “blockbuster status” for Carvykti in 2025, Legend CEO Ying Huang said. The...

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Viking Therapeutics taps CordenPharma to manufacture its obesity drugs

Viking Therapeutics has contracted CDMO CordenPharma for a total of $150 million to make billions of clinical and commercial doses of its GLP-1/GIP receptor agonist for weight loss. The Swiss CDMO will...

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Insilico nabs $110M Series E for AI drug discovery after stalling Hong Kong...

Insilico Medicine, part of the first wave of AI-driven drug discovery and development shops, secured a $110 million megaround at a unicorn valuation for its pipeline of 30 treatment candidates. The...

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Ascletis’ not-so-great weight loss data; Vivace’s $35M Series D

Plus, news about Harbour BioMed: Ascletis’ muscle-preserving drug yields limp weight loss data: The Hong Kong-based biotech said its adipose-targeted obesity therapy, called ASC47, demonstrated...

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#CROI25: Merck’s troubled HIV drug heads to regulators; ViiV seeks...

Here are some of the most compelling HIV updates from the annual Conference on Retroviruses and Opportunistic Infections in San Francisco: Merck details Phase 3 wins for two-drug regimen Merck

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Why Gilead could lose its HIV product hopping case

Can Gilead be held accountable for holding back the sale of an HIV drug it allegedly knew was safer than its blockbuster predecessor? That's the question before the California Supreme Court, and the...

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Mallinckrodt and Endo exploring a $7B merger — report

Mallinckrodt Pharmaceuticals and Endo are in talks over a potential merger worth about $7 billion, according to a report from Bloomberg News. The outlet reported that the two specialty pharmas are ...

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Updated: Endo and Mallinckrodt to merge in $6.7B deal

The rumors are true: Endo will combine with Mallinckrodt in a deal worth $6.7 billion. And the new company, which is yet to be named, will be looking to buy new assets ...

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Amgen reports more Phase 3 Uplizna data in myasthenia gravis ahead of FDA filing

Amgen has shared additional Phase 3 data for its rare disease drug Uplizna in myasthenia gravis, bolstering the company’s case for label expansion before a planned FDA filing this quarter. The...

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Montara Therapeutics adds $20M to seed fundraise for neurology pipeline

Montara Therapeutics has raised $20 million in an expanded seed financing to advance a pipeline of preclinical CNS candidates that it says could address safety concerns that have hampered R&D...

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GoodRx CEO Wendy Barnes on the future of the drug discount company

GoodRx has been in a rut. In its almost five years as a public company, its revenue flatlined, and its stock price plunged about 90%. Its founders stepped down as co-CEOs in 2023, and temporary ...

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Endpoints wins SABEW award for Health Tech coverage

When Endpoints News launched our Health Tech newsletter in Fall 2023, it was the first time our newsroom had stepped outside the world of biopharma. It was a bet that our readers, and future...

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Inside Pepper, a New York health tech professional community

Tucked away in a corner of a hip Midtown Manhattan taproom, a group huddled over draft beers on Valentine's Day was smitten — not with each other, but with health tech. On one end of the ...

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Updated: White House pulls Weldon's nomination to lead CDC

The White House pulled the nomination of its proposed CDC Director Dave Weldon just hours before a Senate confirmation hearing was scheduled to begin, a surprise failure in what has been a relatively...

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Canada pitches in to Entos' facility build; Vetter expands in Germany

Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. The Government of Canada is contributing $62 million to Entos...

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Acelyrin, Pliant turn to ‘poison pill’ as Kevin Tang’s Concentra pursues both...

Acelyrin and Pliant Therapeutics, both of which are viewed as takeover targets for Kevin Tang’s Concentra Biosciences, each adopted a “poison pill” on Thursday morning. Acelyrin, a struggling...

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With Hinge Health filing to go public, are we... back?

When Hinge Health filed to go public on Monday afternoon, I’ll admit I was caught off guard. In part, because the stock market had its worst day of the year. But ...

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